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Published by NATIONAL BOOK TRUST,INDIA, 2022
ISBN 10: 9354910483ISBN 13: 9789354910487
Seller: Books Puddle, New York, NY, U.S.A.
Book
Condition: New. pp. 186.
Published by LAP LAMBERT Academic Publishing Jan 2018, 2018
ISBN 10: 6202080086ISBN 13: 9786202080088
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Antibiotics are now considered as a common cause of Drug-Induced Liver Injury (DILI) which is a leading health problem especially in a globally expanding commercialization of new drugs and the increasing exposure of patients to new compounds. Liver injury is characterized by hepatocellular necrosis and degeneration, such as hepatocyte ballooning,as well as mild inflammatory infiltrates within the portal tracts and, less commonly, cholestasis. Liver and kidney concentrate more toxicants than other organs of the body. Almost all organs of the body have the ability to transform the xenobiotic substances but the major drug or xenobiotic metabolizing enzymes are present mainly in the liver.Liver is actively involved in metabolic functions, detoxification and secretory functions in the body, and its disorders are numerous with no effective remedies. Detoxification of a variety of drugs and xenobiotics occurs in liver and liver is capable of acting as a blood reservoir. Antibiotic-induced hepatotoxicity can often be detected early from elevations in serum enzyme levels.Various types of drug induced liver diseases are liver damage, acute fatty infiltration, cholestatic and liver cirrhosis. 68 pp. Englisch.
Published by Edizioni Sapienza Okt 2022, 2022
ISBN 10: 6205228238ISBN 13: 9786205228234
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Gli antibiotici sono oggi considerati una causa comune di danno epatico indotto da farmaci (Drug-Induced Liver Injury, DILI), che rappresenta un problema sanitario di primo piano, soprattutto in un contesto di espansione globale della commercializzazione di nuovi farmaci e di crescente esposizione dei pazienti a nuovi composti. Il danno epatico è caratterizzato da necrosi e degenerazione epatocellulare, come il ballooning degli epatociti, nonché da lievi infiltrati infiammatori nei tratti portali e, meno comunemente, da colestasi. Il fegato e i reni concentrano più sostanze tossiche rispetto ad altri organi del corpo. Quasi tutti gli organi del corpo hanno la capacità di trasformare le sostanze xenobiotiche, ma i principali enzimi di metabolizzazione dei farmaci o degli xenobiotici sono presenti soprattutto nel fegato. Il fegato è attivamente coinvolto nelle funzioni metaboliche, di disintossicazione e di secrezione dell'organismo, e i suoi disturbi sono numerosi e senza rimedi efficaci. La disintossicazione di una varietà di farmaci e xenobiotici avviene nel fegato e il fegato è in grado di agire come serbatoio di sangue. L'epatotossicità indotta da antibiotici può spesso essere individuata precocemente dagli aumenti dei livelli degli enzimi sierici.Vari tipi di malattie epatiche indotte da farmaci sono il danno epatico, l'infiltrazione grassa acuta, la colestasi e la cirrosi epatica. 64 pp. Italienisch.
Published by Verlag Unser Wissen Okt 2022, 2022
ISBN 10: 6205228203ISBN 13: 9786205228203
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Antibiotika gelten heute als häufige Ursache für arzneimittelinduzierte Leberschäden (Drug-Induced Liver Injury, DILI), die vor allem angesichts der weltweit zunehmenden Kommerzialisierung neuer Arzneimittel und der zunehmenden Exposition von Patienten gegenüber neuen Wirkstoffen ein wichtiges Gesundheitsproblem darstellen. Leberschäden sind gekennzeichnet durch hepatozelluläre Nekrose und Degeneration, wie z. B. die Ballonierung von Hepatozyten, sowie leichte entzündliche Infiltrate in den Pfortaderwegen und, seltener, Cholestase. Leber und Niere konzentrieren mehr Giftstoffe als andere Organe des Körpers. Fast alle Organe des Körpers sind in der Lage, xenobiotische Substanzen umzuwandeln, aber die wichtigsten Enzyme für die Verstoffwechselung von Drogen oder Xenobiotika befinden sich hauptsächlich in der Leber, die aktiv an den Stoffwechselfunktionen, der Entgiftung und den sekretorischen Funktionen des Körpers beteiligt ist und deren Störungen zahlreich sind, ohne dass es wirksame Heilmittel gibt. Die Entgiftung einer Vielzahl von Arzneimitteln und Xenobiotika findet in der Leber statt, und die Leber ist in der Lage, als Blutreservoir zu fungieren. Antibiotika-induzierte Hepatotoxizität lässt sich oft frühzeitig anhand erhöhter Serumenzymwerte erkennen. Verschiedene Arten von arzneimittelinduzierten Lebererkrankungen sind Leberschäden, akute Fettinfiltration, Cholestase und Leberzirrhose. 68 pp. Deutsch.
Published by Edições Nosso Conhecimento Okt 2022, 2022
ISBN 10: 6205228246ISBN 13: 9786205228241
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Os antibióticos são agora considerados como uma causa comum das lesões hepáticas induzidas por drogas (DILI), o que constitui um problema de saúde de primeiro plano, especialmente numa expansão global da comercialização de novos medicamentos e na crescente exposição dos pacientes a novos compostos. A lesão hepática é caracterizada por necrose hepatocelular e degeneração, como o balonamento hepatocitário, bem como leves infiltrados inflamatórios dentro das vias do portal e, menos comumente, colestase. Concentrado hepatocelular e renal mais tóxico do que outros órgãos do corpo. Quase todos os órgãos do corpo têm a capacidade de transformar as substâncias xenobióticas, mas as principais drogas ou enzimas metabolizadoras xenobióticas estão presentes principalmente no fígado. O fígado está activamente envolvido em funções metabólicas, desintoxicação e funções secretas no corpo, e as suas perturbações são numerosas, sem remédios eficazes. A desintoxicação de uma variedade de drogas e xenobióticos ocorre no fígado e o fígado é capaz de actuar como um reservatório de sangue. A hepatotoxicidade induzida por antibióticos pode frequentemente ser detectada precocemente a partir de níveis elevados de enzimas séricas. Vários tipos de doenças hepáticas induzidas por drogas são danos hepáticos, infiltração aguda de gordura, colestésicos e cirrose hepática. 64 pp. Portugiesisch.
Published by Ediciones Nuestro Conocimiento Okt 2022, 2022
ISBN 10: 6205228211ISBN 13: 9786205228210
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Los antibióticos se consideran actualmente una causa común de lesión hepática inducida por fármacos (DILI), que constituye un problema sanitario de primer orden, especialmente en un contexto de expansión mundial de la comercialización de nuevos fármacos y de creciente exposición de los pacientes a nuevos compuestos. La lesión hepática se caracteriza por la necrosis y degeneración hepatocelular, como el abombamiento de los hepatocitos, así como por leves infiltrados inflamatorios en los tractos portales y, con menor frecuencia, colestasis. El hígado y el riñón concentran más tóxicos que otros órganos del cuerpo. Casi todos los órganos del cuerpo tienen la capacidad de transformar las sustancias xenobióticas, pero las principales enzimas metabolizadoras de fármacos o xenobióticos están presentes principalmente en el hígado.El hígado participa activamente en las funciones metabólicas, la desintoxicación y las funciones secretoras del cuerpo, y sus trastornos son numerosos y sin remedios eficaces. La desintoxicación de una variedad de fármacos y xenobióticos se produce en el hígado y éste es capaz de actuar como depósito de sangre. La hepatotoxicidad inducida por los antibióticos puede detectarse a menudo de forma precoz a partir de las elevaciones de los niveles de enzimas séricas.Varios tipos de enfermedades hepáticas inducidas por fármacos son el daño hepático, la infiltración grasa aguda, la colestásica y la cirrosis hepática. 64 pp. Spanisch.
Published by Editions Notre Savoir Okt 2022, 2022
ISBN 10: 620522822XISBN 13: 9786205228227
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Les antibiotiques sont désormais considérés comme une cause fréquente de lésions hépatiques d'origine médicamenteuse (DILI), qui constituent un problème de santé majeur, en particulier dans un contexte d'expansion mondiale de la commercialisation de nouveaux médicaments et d'exposition croissante des patients à de nouveaux composés. Les lésions hépatiques sont caractérisées par une nécrose et une dégénérescence hépatocellulaires, telles que le gonflement des hépatocytes, ainsi que par de légers infiltrats inflammatoires dans les voies portales et, plus rarement, par une cholestase. Le foie et les reins concentrent plus de substances toxiques que les autres organes du corps. Presque tous les organes du corps ont la capacité de transformer les substances xénobiotiques, mais les principales enzymes de métabolisation des médicaments ou des xénobiotiques sont présentes principalement dans le foie.Le foie participe activement aux fonctions métaboliques, à la détoxification et aux fonctions de sécrétion dans le corps, et ses troubles sont nombreux sans remèdes efficaces. La détoxification d'une variété de médicaments et de xénobiotiques se produit dans le foie et celui-ci est capable d'agir comme un réservoir de sang. L'hépatotoxicité induite par les antibiotiques peut souvent être détectée précocement grâce à l'élévation des taux d'enzymes sériques. Les différents types de maladies du foie induites par les médicaments sont les lésions hépatiques, l'infiltration graisseuse aiguë, la cholestase et la cirrhose du foie. 68 pp. Französisch.
Published by Pharma Med Press, 2018
ISBN 10: 9385433911ISBN 13: 9789385433917
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
Book
Condition: New.
Published by LAP LAMBERT Academic Publishing Sep 2018, 2018
ISBN 10: 3659869287ISBN 13: 9783659869280
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The author has used Coupled Displacement Field method to study the free vibration behavior of Timoshenko beams for linear vibrations and large amplitude vibrations for different boundary conditions such as Hinged-Hinged, Clamped-Clamped and Hinged-Clamped. The author has also published his research work on vibration behavior of structural members like tapered Timoshenko beams, uniform Timoshenko beams resting on elastic foundations, thin and moderately thick plates plates resting on elastic foundations, Taper Thick Plates, Thick plates with central cutouts. Coupled Displacement Field method reduces computational efforts half to the existing energy methods. 72 pp. Englisch.
Published by LAP LAMBERT Academic Publishing Dez 2018, 2018
ISBN 10: 3330005556ISBN 13: 9783330005556
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Apoptosis is a distinctive form of cell death whose function is the deletion of cells in normal development,embryogenesis, immune function and tissue growth but which can also induced by pathological stimuli.Toxicological interactions have been broadly defined as 'a circumstance in which exposure to two or more chemicals results in a qualitatively or quantitatively altered biological response relative to that predicted from the action of a single chemical'.All chemicals in the industrial waste are toxic to animals and may cause death or sub-lethal pathology of the liver,kidney,heart,reproductive systems, respiratory systems and nervous systems.The liver and kidney are especially vulnerable to many toxic substances. These pollutants cause problems only when human activities lead to their presence in excessively high levels.Toxic substances damage biological systems, disturb the functioning of biochemical processing and results in detrimental and even fatal effects.Apoptosis has been reported to be a self protective phenomenon of organisms in complex patho-physiological conditions during sepsis, allowing the body to down regulate the intense inflammatory response caused by necro 116 pp. Englisch.